
Molecular Ageing
The study of molecular ageing is a cutting-edge discipline, providing a novel lens through which to understand and treat age-related decline. This course offers a comprehensive introduction to the biological drivers of ageing, from evolutionary theories to the molecular hallmarks that define the biological clock. Participants will explore the mechanisms of DNA repair, the impact of oxidative stress, and emerging therapeutic frontiers, including senolytics and rejuvenation technologies moving from the laboratory into clinical consideration.
What you’ll learn
- Understand the core biology of ageing and the primary evolutionary theories such as antagonistic pleiotropy.
- Learn the molecular “Hallmarks of Ageing,” including cellular senescence, loss of proteostasis, and mitochondrial dysfunction.
- Gain insight into nutrient-sensing pathways (mTOR, AMPK) and how interventions such as caloric restriction influence lifespan.
- Understand the mechanisms of DNA damage and repair, and how they relate to accelerated ageing syndromes such as Werner syndrome.
- Learn about the latest therapeutic frontiers, including senolytics, partial rejuvenation, and reprogramming.








