There are a number of diseases which are brought about by genetics. This includes over 10,000 monogenic diseases which come about as a result of mutations within individual genes. CRISPR-Cas9 holds a lot of promise as it allows for the repair of genetic defects that are directly responsible for such diseases. In humans, CRISPR/Cas programmable toolkit allows for the precise DNA base editing without the need for cleaving the DNA double-helical strand or the need for a template DNA strand. It also enables the accurate replacement of a DNA section with a synthesised sequence. Its scalability and versatility in genome editing have contributed to its growth as a subject of research in molecular biology and therapeutics.

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