CRISPR: Revolutionising Genome Editing

This advanced-level course is designed to develop an understanding of complex concepts related to genomics, particularly CRISPR/Cas technology and its applications in drug discovery, therapeutics and much more.

Starts 17th May 2022

About This Course

This course provides in-depth knowledge of CRISPR/Cas technology and various concepts in genomics such as cell manipulation, DNA repair, gene cloning, reverse transcriptase, and several others. In addition to advanced-level learning on CRISPR/Cas9 system, this course provides an overview of other CRISPR systems and variants. The limitations and challenges of the technology are discussed, along with its prospects to provide a complete overview of the topic to the learners. Various applications of CRISPR/Cas9 technology have been discussed including drug discovery, therapeutics, agriculture, animal farming, biofuels, and gene drive mechanisms. The course also includes CRISPR/Cas-based COVID detection and therapeutic approaches. A dedicated module in this course will help you to learn how to design your own CRISPR experiment so that the knowledge gained from the course can be translated to laboratory settings. Commonly used CRISPR tools, software, and obtaining gene sequences from the NCBI database have been elaborated to assist researchers with their CRISPR-based experiments. The course also discusses the career opportunities in this field, the key companies using the technology, and the skills that can help to build a successful career in genome editing.
CPD ACCREDITED

Who Is This Course For

This advanced course is designed for a wide range of professionals with a background in bioscience and preferably with a basic knowledge of CRISPR/Cas technology. Undergraduate or graduates and postgraduate scholars, researchers, academicians such as lecturers and professors, investors or venture capitalists, policymakers, and other industry professionals who are capable of self-learning are likely to benefit from this course. The course will also be beneficial to those looking for career opportunities in the field of CRISPR/Cas technology and genomics.

What you'll learn

  • Learn complex and advanced concepts related to genomics and CRISPR/Cas technology
  • Explore the diverse applications of CRISPR/Cas technology
  • Learn about the ethical issues and lesser-known facts of CRISPR/Cas technology
  • Learn to design your own CRISPR experiment
  • Become aware of the career opportunities in this field

Meet Your Instructor

Dr. Christos Evangelou

PhD in Cancer Biology, Division of Molecular and Clinical Cancer Sciences, University of Manchester, UK. Areas of expertise include cancer immunology, melanoma research, cancer immunotherapy, and mechanisms of immunotherapy resistance. During my PhD research, I studied the role of chronic inflammation and the cytokine IFN-gamma in adaptation and immunotherapy resistance in melanoma. By integrating high-throughput transcriptomic analyses and employing various cancer cell lines and animal models, I have developed methods to predict response to immunotherapy in melanoma patients. During my research, I have used the CRISPR/Cas9 system to knockout genes in human and mouse cell lines to assess the role of certain genes in immunotherapy resistance in melanoma.

Dr. Veronica Hughes

Veronica Hughes received her PhD in medical science from the University of Florida. Her primary interest was cancer metastasis, dysregulation of the tumour microenvironment, and analysis of clinical trial design. Additionally, she engaged in the development of novel small animal models.

Dr. Matthias Schröder

PhD in Immunology at the Division of Immunopharmacology of the University Clinic of Frankfurt am Main. Involved in basic and applied research for immunological interventions to treat cancer for 13 years. Matthias used a high-throughput CRISPR/Cas9 approach to generate a library of knockout cells that could be differentiated in immunosuppressive cells to investigate potential loss of function situations. Currently involved in the development of fusion proteins to activate receptors of the TNF-superfamily (CD40, CD27 etc.) at a small German Biotech company as Head of Assay Development.

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