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Stem Cell Technology

This course explores the fundamental principles of stem cell biology, including stem cell potency, embryonic, adult and induced pluripotent stem cells (iPSCs). Learners will study cellular reprogramming, directed differentiation, organoid technology, CRISPR genome editing, quality control and GMP manufacturing. The course also examines regulatory requirements, ethical considerations and current clinical applications of stem cell technologies in regenerative medicine.

What you’ll learn
  • Understand the different types of stem cells and the hierarchy of potency, from totipotent to multipotent.
  • Learn the techniques for generating iPSCs and the epigenetic remodelling involved in cellular induction.
  • Gain insight into 3D culture systems and the engineering of brain, gut, and liver organoids.
  • Understand how CRISPR is used for genome engineering in stem cells and the correction of disease-specific mutations.
  • Learn about quality control markers, genomic stability, and the regulatory frameworks of the FDA, EMA, and MHRA.
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Scientific Writing

This course is a guide to scientific writing. The course touches upon different facets and types of scientific writing and presents a succinct overview of the different aspects that need to be considered while engaging in scientific writing activities.

What you’ll learn
  • Learn about the appropriate use of scientific terminology, units, and illustrations.
  • Gain insight into experimental research, data collection, and data analysis.
  • Learn how to conduct a literature search.
  • Get to know about various forms of scientific writing such as structuring a thesis and drafting research manuscripts for publication.
  • Become aware of the ethical and plagiarism issues in scientific writing.
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Molecular Biology Techniques

This course is a beginner’s guide to the various experimental techniques used in molecular biology research. To conduct laboratory research in molecular biology, a researcher must be proficient in basic wet lab techniques. This course provides practical guidance on the key concepts behind these techniques and teaches learners how to perform them in laboratory settings.

What you’ll learn
  • The basic concepts underlying various molecular biology techniques.
  • How to prepare bacterial cell cultures, perform transformations, and screen transformants.
  • How to isolate nucleic acids from different sources and their purification techniques.
  • An overview of analytical techniques, including protein and nucleic acid sequencing.
  • The role of recombinant DNA technology in advancing animal and plant biotechnology.
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Creating Knock-out and Knock-in Using CRISPR/Cas9

This advanced course is designed for researchers planning gene knock-out and knock-in experiments using CRISPR/Cas9 across different cell lines. Divided into two segments—‘Creating Knock-out in E. coli’ and ‘Creating Knock-in Cell Lines’—it covers essential CRISPR/Cas9 concepts and prepares learners with the techniques and tools needed for successful lab execution.

What you’ll learn
  • Learn about the basic concepts of CRISPR/Cas9 technology.
  • Gain insight into the applications of CRISPR/Cas9 knock-out and knock-in cell lines.
  • Learn how to construct plasmids, donors, and guide vectors.
  • Learn how to transfect cells via electroporation.
  • Gain insight into mutagenesis and plasmid curing processes.
  • Learn about analytical methods, such as genotyping and direct sequencing, used to validate gene edits.
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Vaccine Design

Vaccines have led to the eradication of diseases such as polio, but how are they designed? This course explores how vaccines are developed to ensure both effectiveness and safety.

What you’ll learn
  • Understand the importance of vaccines and the immunology behind how they work.
  • Learn about the stages of the drug development process, including clinical approval and post-approval safety monitoring.
  • Gain insight into safety regulations and ethical considerations in vaccine use.
  • Explore how vaccines can be optimised and learn about emerging vaccine technologies.
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Transcriptomics: Unravelling the Transcriptome

This intermediate-level course explores the concepts of the transcriptome with its technology and addresses how these concepts can help to reveal the genetic architecture of a trait.

What you’ll learn
  • Learn basic and key concepts of transcriptomics, transcription factors, and regulation of gene transcription.
  • Gain insight into transcriptome profiling of embryos, and for autoimmune disorders and chronic inflammatory diseases.
  • Explore the applications of transcriptomics in pest management and plant breeding.
  • Understand how transcriptomics can help to explore the genetic architecture of a trait.
  • Get updated on the career opportunities in the field of transcriptomics.
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Tissue Engineering

Over the past 30 years, tissue engineering has undergone a significant transformation, focusing on the regeneration of functionalised tissue for medical applications. This course covers all aspects of tissue engineering, including cell biology, biomaterial scaffolds, and cell bioreactors. In addition, students will gain insight into the latest advancements in the field.

What you’ll learn
  • Gain an understanding of the core concepts of tissue engineering, as well as the needs and challenges faced by researchers
  • Learn fundamental cell culture techniques for cell suspension
  • Identify the advantages and disadvantages of different types of biomaterial scaffolds
  • Explore research strategies for developing and characterising materials and investigating cell–material interactions
  • Describe different types of bioreactors used in tissue engineering applications
  • Develop an understanding of selected research studies across various medical fields
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Proteomics

This course provides an all-around understanding of proteomics from the basic structure of proteins, the typical workflow in a proteomics experiment, the techniques and instruments used in proteomics and considerations in analysing data obtained from proteomics experiments.

What you’ll learn
  • Understand protein structure and functions.
  • Learn how to design a proteomic experiment.
  • Understand real-life applications of proteomics.
  • Understand how proteins can be separated for analysis.
  • Learn how a mass spectrometer instrument works.
  • Gain insight into the analysis of proteomics data.
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Principles of Biochemistry

This course introduces the principles of biochemistry, beginning with the biological building blocks of cells and progressing to fundamental metabolic signalling cascades, exploring how these pathways can be utilised in cancer therapy.

What you’ll learn
  • Understand the basics of protein structure and protein folding.
  • Appreciate the many different sources of energy for cell metabolism.
  • Be able to draw enzymatic reactions.
  • Gain an insight into key biochemical reactions in the cells.
  • Become familiar with key cell signalling pathways.
  • Understand the importance of cell biochemistry in cancer therapy.
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Pharmacology

Pharmacology is the study of the effects of drugs on living systems and plays a crucial role in drug discovery. This course offers an overview of the field, covering essential concepts such as pharmacodynamics and pharmacokinetics, which are fundamental in researching new treatments.

What you’ll learn
  • What pharmacology is and why it matters.
  • The differences between pharmacodynamics and pharmacokinetics.
  • How drugs bind and interact with receptors in the body.
  • An introduction to the immune system and its role in pharmacology.
  • Key information about painkillers, antibiotics, antivirals, and antifungal medications.
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Next Generation Sequencing (NGS)

This intermediate-level course provides a thorough overview of the field of Next Generation Sequencing, covering its properties, strengths, major applications, and an overview of a typical sequencing workflow.

What you’ll learn
  • Review the genetic concepts required to understand NGS and explore the development of the first generations of DNA sequencing methods.
  • Explore and understand the motivation and fundamental basis of NGS, current and emerging sequencing technologies, alongside their advantages and potential biases that may affect their accuracy.
  • Learn the typical workflow of NGS, from sample preparation and high-quality library creation to post-sequencing quality control and data management.
  • Gain familiarity with the major applications of NGS, which include, among others, transcriptomic analysis by RNA-Seq, genomic variation discovery by Whole Genome Sequencing, and epigenomics.
  • Discover what the future of NGS may hold by covering the current changing landscape of NGS and the rapid evolution of data analysis bioinformatics tools.
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Molecular Microbiology

Molecular microbiology is a rapidly advancing field of science, with a growing demand to understand the omnipresent microbes that influence our daily lives at the sub-cellular level. This will be the primary focus of the course.

What you’ll learn
  • Learn the principles of microbial life at the sub-cellular level.
  • Understand how changes in the genome and genomic analyses can be applied in real-world scenarios.
  • Get familiar with various molecular-genetic techniques used in diagnostics and epidemiology.
  • Recognise the practical applications and promising career opportunities in molecular microbiology.
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