Biophysics is an interdisciplinary field (Physics, Pharmacology, Chemistry etc) which applies theories and methods of Physics to study and understand biological systems. How a cell moves and how molecules of life (sugars, proteins, DNA) are structured have been tackled by biophysicists.
Biophysicists rely on their quantitative training to develop tools in order to unveil biological mysteries – a better understanding of Life allows a better tackling of disease and guides therapeutics. Present applications of Biophysics include:
- Biological molecules structural analysis: Watson and Crick were awarded the Medicine Nobel Prize in 1962 for their discovery of the molecular structure of DNA, the genetic code of Life. They used X-ray diffraction patterns (X-rays used to determine biological molecules “locked in crystals”) to uncover the famous double DNA helix structure.
- Computer modeling: to visualize and manipulate biological molecules for drug development. It has been useful in understanding how viruses such as COVID-19 binds to the surface of our cells and mediate subsequent infection. Modeling how protein mutation(s) can enhance tumour growth has also benefitted from this tool.
- Neuroscience: computational neural networks that imitate how the brain and nervous system work in the body have shed light on how nerve cells communicate and break down in neurodegenerative diseases.
- Biomaterials: have revolutionized bioengineering and tissue engineering to repair damaged tissues in affected patients. An array of materials are used for prosthetics, artificial joints, hip replacements: silicone rubber for finger joints, bioglass for spine cages, PVC for facial prostheses. Biomaterials need to compatible with the environmental conditions of the organs or cells they are inserted in – corrosion resistant, wear resistant and not trigger any side effects in patients.
- Imaging: Internal body images are produced by MRI (magnetic resonance imaging), CT (computerized tomography) and PET (positron emission tomography) scans. These commonly used techniques have been developed by biophysicists and used for screening/diagnosis in medical settings.
Featured Courses
The CPD accredited courses are carefully crafted to help you gain in-depth knowledge on a topic of your interest.
Next Generation Sequencing (NGS)
This intermediate-level course provides a thorough overview of the field of next-generation sequencing, from its properties and strength and its major applications, to an overview of a typical sequencing workflow.
Molecular Microbiology
Molecular microbiology is a very progressive field of science, there is an enormous demand to understand the omnipresent microbes influencing our everyday life on sub-cellular level, which will be subject of this course.
Gene Therapy
Gene therapy is one of the youngest disciplines providing a novel way into treating diseases.
Cancer Biology: Exploring the Molecular and Genetic Aspects
This is an intermediate-level course that explores the molecular and genetic basis of cancer, its evolution, and cancer immunology.
Neuroscience
Neuroscience is one of the most advanced and fastest growing sciences. The beginning of the 21st century has seen huge developments in techniques to study and understand how the brain works.
CRISPR: Revolutionising Genome Editing
This advanced-level course is designed to develop an understanding of complex concepts related to genomics, particularly CRISPR/Cas technology and its applications...
- Medical applications: Biophysicists have tackled life-threatening conditions, examples include: the implantation of a one-way valves (needed to ensure blood flow in a single direction) to replace a non-functional one in the heart or using a cardiac defibrillator to deliver electric current to irregular heartbeats.
Biophysicists usually work in academic research labs, hospitals or industrial engineering companies to conduct 3D biological modeling, develop diagnostic tests and unveil biological secrets. Beyond these traditional roles, they also advise governmental bodies and practice law in domains including intellectual property.
